Entries by labadmin

New cancer treatment uses enzymes to boost immune system and fight back

In our most recent paper, we show that administration of a pharmacologically optimized enzyme (PEGylated kynureninase; hereafter referred to as PEG-KYNase) that degrades Kyn into immunologically inert, nontoxic and readily cleared metabolites inhibits tumor growth. Enzyme treatment was associated with a marked increase in the tumor infiltration and proliferation of polyfunctional CD8+ lymphocytes. We show that PEG-KYNase […]

GRA George Delidakis wins Poster Prize at EMBO Antibodies Conference

GRA George Delidakis recently attended the EMBO Antibody and Complement: Effector functions, Therapies and Technologies Conference in Girona, Spain and was awarded one of two Poster Awards. The Conference was attended by an international group of faculty, students, and scientists from the biotech industry who work on understanding the diverse and complex roles of antibodies […]

Undergraduate Researcher Justin Mirazee awarded ThinkSwiss Research Scholarship and URF Fellowship

Justin Mirazee, Undergraduate Researcher, was awarded the ThinkSwiss Research Scholarship to assist research in Dr. Sai Reddy’s lab at ETH-Zürich for Summer 2018. Justin will be learning how to use CRISPR-Cas9 to modify antibody expression in murine hybridoma cell lines and engineer other complex proteins such as chimeric antigen receptors (CARs) for immunotherapy. In addition, […]

Dr. Everett Stone Named Emerging Inventor of the Year

Congratulations to Dr. Everett Stone, Emerging Inventor of the Year! On November 2, 2017, the UT Austin Office of Technology Commercialization hosted the 7th Annual Inventor Award Ceremony & Reception. The prestigious Inventor of the Year Award, honors a researcher whose discoveries have made a significant impact, and the Emerging Inventor of the Year Award, acknowledges a researcher […]

Undergraduate Researcher Justin Mirazee wins a Fall Undergraduate Research Symposium Best Presentation Award!

Congratulations to Undergraduate Researcher Justin Mirazee who recently won the Fall Undergraduate Research Symposium Award for Best Presentation in his Session. Justin is working with Graduate Researcher Wissam Charab and Undergraduate Researcher Matthew Rosenbeger. The Fall Undergraduate Research Symposium is a chance for students to present a highlight reel of their research at UT to underscore […]

Dr. Georgiou Delivers Prestigious Global Distinguished Lecture at KAIST

Dr. Georgiou was selected to deliver the Prestigious 2017 Global Distinguished Lecture in the Department of Chemical and Biomolecular Engineering at KAIST. His lecture Discovery, Preclinical and Clinical Development of Therapeutic Treatment for Cancer Therapy focused on the pioneering methods he has developed to engineer therapeutic enzymes capable of degrading specific amino acids related to […]